Child maltreatment is a significant public health problem. It is also a preventable one. As demonstrated in the preceding presentations, identification of risk factors for adverse childhood experiences (ACEs) and their relationships to subsequent health problems is an important step in understanding the impact of child maltreatment on adult health and wellbeing. Further, identifying the contextual influences that may ameliorate the health of individuals exposed to ACEs is also paramount. As such, the child maltreatment field has begun to prioritize protective factors for children and families. The Centers for Disease Control and Prevention’s (CDC) Essentials for Childhood framework represents CDC’s vision for the prevention of child maltreatment by promoting strategies to assure safe, stable, nurturing relationships and environments for all children. This presentation will review the rationale for this approach and its key components, placing a premium on data informed action and the promotion of contexts that support safe, stable, nurturing relationships and environments through norms change, programs, and policies.